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RAET1E Mouse

目录号 : GP24321

Retinoic Acid Early Transcript 1E Mouse Recombinant

RAET1E Mouse Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

RAET1E produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 207 amino acids (29-227a.a.) and having a molecular mass of 23.5kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).RAET1E is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Sf9,Insect cells.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms RAE-1-epsilon;Retinoic acid early-inducible protein 1-epsilon; Raet1e.
Amino Acid Sequence LDDAHSLRCNLTIKDPTSAD LPWCDVKCSV DEITILHLNN INKTMTSGDP GKMANATGKC LTQPLNDLCQ ELRDKVSNTKVDTHKTNGYP HLQVTMIYPQ SQGQTPSATW EFNISDSYFF TFYTENMSWR SANDESGVIM NKWKDDGDLV QQLKYFIPQC RQKIDEFLKQ SKEKPRSTSR SPSITQLTST SPLPPPSHSL EHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation RAET1Eprotein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol.

Introduction

RAET1E is a member of the MHC class I family. MHC class I family contains main histocompatibility complex (MHC) class I-related genes positioned in a cluster on chromosome 6q24.2-q25.3. RAET1E and RAET1G protein are different from other RAET1 proteins since they have type I membrane-spanning sequences at their C termini instead glycosylphosphatidylinositol anchor sequences.RAET1E acts as a ligand for NKG2D receptor, expressed on the surface of numerous types of immune cells, involves in innate adaptive immune reactions.RAET1E delivers signals to NK cells and advances tumor immune surveillance by inducing the growth of anti-tumor cytotoxic lymphocyte.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.