Protein A
目录号 : GP24668葡萄球菌蛋白A重组体
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 95.0% as determined by RP-HPLC. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Immunoglobulin G-binding protein A; IgG-binding protein A; Staphylococcal protein A; SPA. | ||
Stability | SPA should be stored at -20°C . | ||
Biological Activity | Greater than 95.0% binding activity to human IgG. | ||
Formulation | The protein solution contains no additives. |
Protein A is a cell wall protein deriving from Staphylococcus aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The recombinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin).
Greater than 95.0% binding activity to human IgG.
SPA should be stored at -20°C .