PHF5A Human
目录号 : GP24178PHD Finger Protein 5A Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | PHD finger protein 5A; bK223H9.2; INI; Rds3; SAP14b; SF3b14b; PHD finger-like domain-containing protein 5A; PHD finger-like domain protein 5A; Splicing factor 3B-associated 14 kDa protein; PHF5A. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAKHHPD LIFCRKQAGV AIGRLCEKCD GKCVICDSYV RPCTLVRICD ECNYGSYQGR CVICGGPGVS DAYYCKECTI QEKDRDGCPK IVNLGSSKTD LFYERKKYGF KKR. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | The PHF5A solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.15M NaCl, 10% glycerol and 1mM DTT. | ||
PHD Finger Protein 5A, also known as PHF5A, is a part of the PHD-finger superfamily and acts as a chromatin-associated protein. PHF5A is a subunit of the splicing factor 3b protein complex which along with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intronбпs branch site in a sequence-independent way and anchors the U2 snRNP to the pre-mRNA. PHF5A holds a PHD-finger-like domain which is flanked by highly basic N- and C-termini.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.