P Selectin Human
目录号 : GP24253P-selectin Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95% as determined by SDS-PAGE. Single band on Western Blot. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered liquid formulation. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | P-selectin; Granule membrane protein 140; GMP-140; PADGEM; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; CD62 antigen-like family member P; CD62P antigen; SELP; GMRP; GRMP; CD62; PSEL; CD62P; GMP140; FLJ45155. | ||
| Stability | Store at 4°C if entire vial will be used within 1-2 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles. | ||
| Formulation | P-Selectin is supplied in 50% Glycerol. | ||
P-Selectin also called Platelet Alpha-Granule Membrane Protein, CD62, and Granulocyte Membrane Protein GRMP belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. Pselectin is expressed transiently on the surface of activated platelets and endothelial cells. P-Selectin is a 140 kDa protein which is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. P-Selectin is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Levels of P-Selectin may be elevated in a number of pathological conditions.
P-Selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments.The biological activity of this product has not yet been tested.
Store at 4°C if entire vial will be used within 1-2 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.