Ostreolysin
目录号 : GP24112Ostreolysin Pleurotus Ostreatus Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 98.0% as determined by:(a) Analysis by Gel filtration analysis.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Amino Acid Sequence | The N-terminal amino sequence is Ala-Tyr-Ala-Gln-Trp-Val. | ||
| Solubility | It is recommended to reconstitute the lyophilized Ostreolysin in sterile 0.4% NaHCO3, not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Pleurotus Ostreatus Ostreolysin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon C between 2-7 days and for future use reconstituted Ostreolysin should be stored at 4°C below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze-thaw cycles. | ||
| Biological Activity | Ostreolysin has potent anti-carcinogenic activity in several colon cancer cell lines. | ||
| Formulation | The Ostreolysin protein was lyophilized from a concentrated (1mg/ml) solution with 0.02% NaHCO3. | ||
Ostreolysin is extracted from Pleurotus ostreatus (oyster mushroom). It is a pore forming protein, which contains a lytic part to both cholesterol and sphingomyelin containing membranes. Because of their cholesterol content and the appearance of ostreolysin in the detergent resistant membranes, ostreolysin is cytotoxic towards the ovary cells of Chinese hamster. It seems that Ostreolysin spots a rich lipid cholesterol phase, presumably the liquid ordered phase.
Ostreolysin has potent anti-carcinogenic activity in several colon cancer cell lines.
Lyophilized Pleurotus Ostreatus Ostreolysin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon C between 2-7 days and for future use reconstituted Ostreolysin should be stored at 4°C below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze-thaw cycles.