ORC6 Human
目录号 : GP24103Origin Recognition Complex, Subunit 6 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Origin Recognition Complex Subunit 6; Origin Recognition Complex Subunit 6 Homolog-Like (Yeast); ORC6L. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMGSELIG RLAPRLGLAE PDMLRKAEEY LRLSRVKCVG LSARTTETSS AVMCLDLAAS WMKCPLDRAY LIKLSGLNKE TYQSCLKSFE CLLGLNSNIG IRDLAVQFSC IEAVNMASKI LKSYESSLPQ TQQVDLDLSR PLFTSAALLS ACKILKLKVD KNKMVATSGV KKAIFDRLCK QLEKIGQQVD REPGDVATPP RKRKKIVVEA PAKEMEKVEE MPHKPQKDED LTQDYEEWKR KILENAASAQ KATAE | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | The ORC6 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 2mM DTT and 40% glycerol. | ||
ORC6 is a member of the origin recognition complex (ORC) which is a highly conserved heterohexameric protein complex. ORC contacts to DNA at or near sites of initiation of DNA replication and all of its six subunits are vital for initiation of DNA replication. Additionally, ORC takes part in regulation of gene expression in response to stress. ORC6 is regularly expressed throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a primary complex at which point ORC6 and ORC1 assemble.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.