OPTC Human
目录号 : GP24101Opticin Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Opticin; Oculoglycan; OPT. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSASLPRKE RKRREEQMPR EGDSFEVLPL RNDVLNPDNY GEVIDLSNYEELTDYGDQLP EVKVTSLAPA TSISPAKSTT APGTPSSNPT MTRPTTAGLL LSSQPNHGLP TCLVCVCLGSSVYCDDIDLE DIPPLPRRTA YLYARFNRIS RIRAEDFKGLTKLKRIDLSN NLISSIDNDA FRLLHALQDL ILPENQLEAL PVLPSGIEFLDVRLNRLQSS GIQPAAFRAM EKLQFLYLSD NLLDSIPGPL PLSLRSVHLQ NNLIETMQRD VFCDPEEHKHTRRQLEDIRL DGNPINLSLF PSAYFCLPRL PIGRFT. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | OPTC protein solution (0.5mg/ml) containing 20mM Tris-HCl(pH8.0) and 10% glycerol. | ||
Opticin also known as OPTC is a member of the class III of the smallleucine-rich repeat protein (SLRP)family. Members of this family are usually linked with the extracellularmatrix. OPTC is attended in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, opticnerve, choroid, retina, and fetal liver. OPTC might noncovalently bind collagenfibrils and regulate fibril morphology, spacing and organization. OPTC is mappedto a an area of chromosome 1 which is linked with the inherited eye diseasesage-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa(AXPC1).
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.