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NCR3 Human

目录号 : GP24018

Natural Cytotoxicity Triggering Receptor 3 Human Recombinant

NCR3 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

NCR3 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 141 amino acids (19-138 a.a) andhaving a molecular mass of 15.3kDa.NCR3 is fused to a 21 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 90% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Natural Cytotoxicity Triggering Receptor 3; LY117; 1C7; LymphocyteAntigen 117; Activating Natural Killer Receptor P30; Natural Killer CellP30-Related Protein; NK-p30; NKp30; CD337; MALS; Activating NK-A1 Receptor; CD337Antigen; NKP30.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MLWVSQPPEI RTLEGSSAFL PCSFNASQGR LAIGSVTWFR DEVVPGKEVR NGTPEFRGRLAPLASSRFLH DHQAELHIRD VRGHDASIYV CRVEVLGLGV GTGNGTRLVV EKEHPQLGAG T
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Formulation NCR3 protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

Introduction

CytotoxicityTriggering Receptor 3 also known as NCR3 is a natural cytotoxicity receptor(NCR) which assists NK cells in the lysis of tumor cells. Moreover, NCR3interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotidepolymorphism in the 5' untranslated region of NCR3 has been related with mildmalaria suceptibility. Three transcript variants encoding various isoforms havebeen found for this gene.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.

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