N,N-Diethylpentylone (hydrochloride)
目录号 : GC44277
An Analytical Reference Standard
Cas No.:17763-15-4
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
N,N-Diethylpentylone (hydrochloride) is an analytical reference standard that is structurally classified as a cathinone. Its physiological and toxicological actions have not been characterized. This compound is for the forensic analysis of samples that may contain this compound.
| Cas No. | 17763-15-4 | SDF | |
| Canonical SMILES | O=C(C(CCC)N(CC)CC)C1=CC(OCO2)=C2C=C1.Cl | ||
| 分子式 | C16H23NO3•HCl | 分子量 | 313.8 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 1 mg/ml | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
||
| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 3.1867 mL | 15.9337 mL | 31.8674 mL |
| 5 mM | 0.6373 mL | 3.1867 mL | 6.3735 mL |
| 10 mM | 0.3187 mL | 1.5934 mL | 3.1867 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Comparison of the efficacy of ambroxol hydrochloride and N -acetylcysteine in the treatment of children with bronchopneumonia and their influence on prognosis
Exp Ther Med 2020 Dec;20(6):130.PMID:33082862DOI:10.3892/etm.2020.9260.
The aim of the present study was to compare the efficacy of ambroxol hydrochloride and N-acetylcysteine in the treatment of children with bronchial pneumonia and their influence on prognosis. A total of 120 children with bronchial pneumonia, admitted to The Affiliated Yantai Yuhuangding Hospital of Qingdao University from July 2015 to August 2018, were enrolled in the study. Among them, 58 children were treated with N-acetylcysteine and comprised the experimental group, and 62 children were treated with ambroxol hydrochloride and comprised the control group. Children's physical signs (such as fever, short breath, cough and pulmonary rales) and the adverse reactions to treatment were observed, and the disappearance time of the signs was recorded. In addition, the cellular immune function indicators and the quality of life after treatment were investigated. There was no significant difference in clinical data between the two groups (P>0.05). The effective rate in the experimental group was significantly higher than that in the control group (P<0.05). The disappearance time of symptoms, such as fever, cough, asthma and rales in the lung, was significantly shorter in the experimental group than that in the control group (P<0.05). The hospitalization time of patients in the experimental group was shorter than that in the control group (P<0.05). After treatment, immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM) and complement C3 were significantly increased in the experimental group (P<0.01), and the IgA and IgG in the experimental group were significantly higher than those in the control group (P<0.01). The incidence of adverse reactions in the experimental group was significantly lower than that in the control group (P<0.05). In conclusion, N-acetylcysteine has a significant effect on the treatment of bronchopneumonia in children providing a quick relief from symptoms, such as lung rales, and therefore is worthy of use in clinic.
Photocatalytic degradation of tetracycline hydrochloride with g-C3N4/Ag/AgBr composites
Front Chem 2022 Nov 14;10:1069816.PMID:36451930DOI:10.3389/fchem.2022.1069816.
Graphite carbon nitride (g-C3N4), as a polymer semiconductor photocatalyst, is widely used in the treatment of photocatalytic environmental pollution. In this work, a Z-scheme g-C3N4/Ag/AgBr heterojunction photocatalyst was prepared based on the preparation of a g-C3N4-based heterojunction via in-situ loading through photoreduction method. The g-C3N4/Ag/AgBr composite showed an excellent photocatalytic performance in the degradation of tetracycline hydrochloride pollutants. Among the prepared samples, g-C3N4/Ag/AgBr-8% showed the best photocatalytic ability for the degradation of tetracycline hydrochloride, whose photocatalytic degradation kinetic constant was 0.02764 min-1, which was 9.8 times that of g-C3N4, 2.4 times that of AgBr, and 1.9 times that of Ag/AgBr. In the photocatalytic process, •O2- and •OH are main active oxygen species involved in the degradation of organic pollutants. The photocatalytic mechanism of g-C3N4/Ag/AgBr is mainly through the formation of Z-scheme heterojunctions, which not only effectively improves the separation efficiency of photogenerated electron-hole pairs, but also maintains the oxidation and reduction capability of AgBr and g-C3N4, respectively.
Crystal structures and other properties of ephedrone (methcathinone) hydrochloride, N-acetylephedrine and N-acetylephedrone
Forensic Toxicol 2019;37(1):224-230.PMID:30636989DOI:10.1007/s11419-018-0436-7.
Purpose: Three compounds obtained from ephedrine were identified and characterized by various instrumental analytical methods. Ephedrone (methcathinone) hydrochloride and its fundamental derivatives N-acetylephedrine and N-acetylephedrone were analyzed as precursors of a cathinone derivative. Methods: The obtained samples were analyzed by gas chromatography coupled with mass spectrometry, nuclear magnetic resonance spectroscopy, infrared and Raman spectroscopy, and X-ray crystallography. Results: The three compounds were confirmed as: N-methyl-2-amino-1-phenylpropan-1-one (methcathinone) hydrochloride, N-acetyl-N-methyl-2-amino-1-phenylpropan-1-one (cathinone derivative), and N-acetyl-N-methyl-2-amino-1-phenylpropan-1-ol (acetyl derivative of ephedrine). Conclusions: X-ray crystallography is especially useful for identifying the new designer drugs and their different precursor forms.
Stability of [(N-piperidine)methylene]daunorubicin hydrochloride and [(N-pyrrolidine)methylene]daunorubicin hydrochloride in solid state
Acta Pol Pharm 2014 May-Jun;71(3):431-8.PMID:25265823doi
The influence of temperature and relative air humidity on the stability of two novel derivatives of daunorubicin: [(N-piperidine)methylene]daunorubicin hydrochloride and [(N-pyrrolidine)methylene]daunorubicin hydrochloride was investigated. The process of degradation was studied by using high-performance liquid chromatography with ultraviolet (UV) detection. The kinetic and thermodynamic parameters of degradation were calculated.
NiFe2O4/g-C3N4 heterostructure with an enhanced ability for photocatalytic degradation of tetracycline hydrochloride and antibacterial performance
Chemosphere 2022 Nov;307(Pt 1):135717.PMID:35863405DOI:10.1016/j.chemosphere.2022.135717.
In this work, NiFe2O4/g-C3N4 heterostructure was prepared and used for the photocatalytic decomposition of tetracycline hydrochloride antibiotic and for inactivation of E. coli bacteria. The fabricated NiFe2O4/g-C3N4 composite displayed enhanced ability for photodegradation of organic pollutants and disinfection activities compared to the bare samples, because of the enhancement of visible light absorbance, heterojunction formation and photo-Fenton process. The optimized sample 10%-NiFe2O4/g-C3N4 has photodegraded 94.5% of tetracycline hydrochloride in 80 min. The active species trapping experiments revels that ·O2-, h+ and •OH are key decomposing species participated in the antibiotic degradation. It is hoped that the present study will provide a better understanding to fabricate efficient photocatalysts for the decomposition of organic pollutants and disinfection of bacteria.