MTCP1 Human
目录号 : GP23967Mature T-Cell Proliferation 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Mature T-Cell Proliferation 1; Mature T-Cell Proliferation-1 Type B1; MTCP-1 Type B1; P13MTCP1; Mature T-Cell Proliferation 1 Isoform P13; p8MTCP1; Protein P13 MTCP-1; C6.1B; p13MTCP1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAGEDVG APPDHLWVHQ EGIYRDEYQR TWVAVVEEET SFLRARVQQI QVPLGDAARP SHLLTSQLPL MWQLYPEERY MDNNSRLWQI QHHLMVRGVQ ELLLKLLPDD | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | MTCP1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl ,10% glycerol and 1mM DTT. | ||
Mature T-Cell Proliferation 1, also known as MTCP1was recognized by involvement in some t(X;14)translocations linked with mature T-cell proliferations.This region has a complex gene structure, with a common promoter and 5' exonspliced to two dissimilarsets of 3' exons which encode two different proteins. It represents the upstream 13 kDa protein whichbelongs to the TCL1 family. In addition, MTCP1 enhances the phosphorylation andactivation of AKT1 and AKT2. MTCP1 is involved in leukemogenesis. Among the diseases associated with MTCP1 are queensland tick typhus,and african tick-bite fever.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.