MREG Human
目录号 : GP23948Melanoregulin Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greaterthan 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Melanoregulin; DSU; Dilute Suppressor Protein Homolog; WDT2;Whn-Dependent Transcript 2. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMGLRDWL RTVCCCCGCE CLEERALPEK EPLVSDNNPY SSFGATLVRDDEKNLWSMPH DVSHTEADDD RTLYNLIVIR NQQAKDSEEW QKLNYDIHTL RQVRREVRNR WKCILEDLGFQKEADSLLSV TKLSTISDSK NTRKAREMLL KLAEETNIFP TSWELSERYL FVVDRLIALD AAEEFFKLARRTYPKKPGVP CLADGQKELH YLPFPSP | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
Formulation | MREG protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
Melanoregulin(MREG) takes part in membrane fusion and in regulating the biogenesis of diskmembranes of photoreceptor rods. MREG is expressed in photoreceptor cells astwo isoforms as a result of alternative splicing. MREG interacts withPeripherin-2, a photoreceptor specific tetraspanin protein which is required topreserve normal cell structure during the renewal process of membrane fusion.Moreover, MREG plays a part in the incorporation of pigments into hair.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.