LAG-1 Human
目录号 : GP21144LAG-1 Human Recombinant (CCL4L1)
Sample solution is provided at 25 µL, 10mM.
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LAG-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 69 amino acids and having a molecular mass of 7.8kDa.The CCL4L1 is purified by proprietary chromatographic techniques.
| Purity | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | C-C motif chemokine 4-like; Lymphocyte activation gene 1 protein; LAG-1; Macrophage inflammatory protein 1-beta; MIP-1-beta; Monocyte adherence-induced protein 5-alpha; Small-inducible cytokine A4-like; CCL4L1; CCL4L; LAG1; SCYA4L1; CCL4L2; SCYA4L2; AT744.2. | ||
| Amino Acid Sequence | APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN. | ||
| Solubility | It is recommended to reconstitute the lyophilized LAG-1 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized LAG-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CCL4L1 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of > 5.0 б┴ 105 IU/mg. | ||
| Formulation | LAG-1 was lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. | ||
CCL4L1 (C-C motif chemokine 4-like) is a member of to intercrine beta (chemokine CC) family. The CCL4L1 protein is similar to CCL4 which inhibits HIV replication in peripheral blood monocytes which express CCR5.
The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of > 5.0 б┴ 105 IU/mg.
Lyophilized LAG-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CCL4L1 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.