IL 2 Human, HEK
目录号 : GP20473Interleukin-2 Human Recombinant, HEK
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95% as obsereved by SDS-PAGE. | Source | HEK. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | T-cell growth factor (TCGF); Aldesleukin; Lymphokine; IL-2. | ||
| Amino Acid Sequence | APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLE EELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT. | ||
| Solubility | It is recommended to reconstitute the lyophilizedIL-2 in sterile PBS containing 0.1% endotoxin-free recombinant HSA. | ||
| Stability | LyophilizedIL-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Biological Activity | The specific activity as determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line) was measured to be 1.57ng/ml. | ||
| Formulation | The IL2 was lyophilized from 0.2µm filtered solution containing 0.76mg/ml protein in 1xPBS. | ||
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
The specific activity as determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line) was measured to be 1.57ng/ml.
LyophilizedIL-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.