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HTLV-1 mosaic

目录号 : GP25436

HTLV-1 Mosaic Recombinant

HTLV-1 mosaic Chemical Structure

规格 价格 库存 购买数量
100μg
¥2,310.00
5-10工作日
500μg
¥9,240.00
5-10工作日
1mg
¥18,900.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

The E.Coli derived recombinant mosaic protein contains the gp21 and gp46 immunodominant regions, 374-400 amino acids and 190-207 amino acids, the MW is 42kDa. The protein is fused with GST at N-terminus.

Product Data

Purity HTLV-1 Mosaic protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC. Source
Phycical Appearance Shipping Condition Shipped with Ice Packs.
Stability HTLV-1 Mosaic although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.
Formulation 60mM NaCl, 50mM Tris-HCl pH 8.0, 0.25% Sarkosil, 50% glycerol and 10mM glutathione.

Introduction

Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).

Purification Method

HTLV-1 Mosaic was purified by proprietary chromatographic technique.

Applications

HTLV-1 Mosaic can be used as an antigen in ELISA and Western Blots. Excellent reagent for correct detection of HTLV infections, with minimal specificity problems.

Stability

HTLV-1 Mosaic although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.