HOXA9 Human
目录号 : GP23672Homeobox A9 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Homeobox A9; HOX1G; Homeobox Protein Hox-1G; Homeodomain Protein HOXA9; Homeobox Protein Hox-A9; Homeo Box A9; HOX1.7; ABD-B; HOX1; HOXA9. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMATTGAL GNYYVDSFLL GADAADELSV GRYAPGTLGQ PPRQAATLAE HPDFSPCSFQ SKATVFGASW NPVHAAGANA VPAAVYHHHH HHPYVHPQAP VAAAAPDGRY MRSWLEPTPG ALSFAGLPSS RPYGIKPEPL SARRGDCPTL DTHTLSLTDY ACGSPPVDRE KQPSEGAFSE NNAENESGGD KPPIDPNNPA ANWLHARSTR KKRCPYTKHQ TLELEKEFLF NMYLTRDRRY EVARLLNLTE RQVKIWFQNR RMKMKKINKD RAKDE. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | The HOXA9 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. | ||
Homeobox A9 (HOXA9) is a member of the Abd-B homeobox family. The HOXA9 protein is a transcription factor with a key role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a distinctive feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. HOXA9 overexpression noticeably expands hematopoietic stem cells. The HOXA9 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which regulates gene expression, morphogenesis, and differentiation. HOXA9 is a sequence-specific transcription factor which is part of a developmental regulatory system, which provides cells with specific positional identities on the anterior-posterior axis. HOXA9 is essential for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.