HLA-DRA Human
目录号 : GP23649Major Histocompatibility Complex Class II DR Alpha Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Major Histocompatibility Complex; Class II; DR Alpha; HLA-DRA1;MHC Class II AntigenDRA; MLRW; Histocompatibility AntigenHLA-DRAlpha; HLAClass II Histocompatibility Antigen; DR Alpha Chain; MHC CellSurface Glycoprotein; HLA-DRA1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MIKEEHVIIQ AEFYLNPDQS GEFMFDFDGD EIFHVDMAKK ETVWRLEEFG RFASFEAQGALANIAVDKAN LEIMTKRSNY TPITNVPPEV TVLTNSPVEL REPNVLICFI DKFTPPVVNV TWLRNGKPVTTGVSETVFLP REDHLFRKFH YLPFLPSTED VYDCRVEHWG LDEPLLKHWE FDAPSPLPET TE | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | HLA-DRA protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. | ||
Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongsto the MHC class II family. HLA-DRA binds peptides derived from antigens whichaccess the endocytic route of antigen presenting cells (APC) and presents themon the cell surface for identification by the CD4 T-cells. The peptide bindingcleft accommodates peptides of 10-30 residues. The peptides presented by MHCclass II molecules are generated mainly by degradation of proteins which accessthe endocytic route, where they are processed by lysosomal proteases and otherhydrolases.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.