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HCV NS5B

目录号 : GP25305

Hepatitis C Virus NS5B Recombinant

HCV NS5B Chemical Structure

规格 价格 库存 购买数量
100μg
¥2,310.00
5-10工作日
500μg
¥9,240.00
5-10工作日
1mg
¥18,900.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

The E.coli derived recombinant protein contains the full length of the NS5B immunodominant regions Genotype 1B and fused to a 6xHis tag at C-Terminus.

Product Data

Purity Protein is >95% pure as determined by SDS-PAGE. Source
Phycical Appearance Shipping Condition Shipped with Ice Packs.
Stability HCV NS5B although stable at 4°C for 1 week, should be stored below -18°C . Please prevent freeze thaw cycles.
Formulation 1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X and 50% Glycerol.

Introduction

HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Purification Method

HCV NS5B Genotype-1b protein was purified by proprietary chromatographic technique.

Applications

HCV NS5B antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.

Stability

HCV NS5B although stable at 4°C for 1 week, should be stored below -18°C . Please prevent freeze thaw cycles.

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