GLTPD1 Human
目录号 : GP23362Glycolipid Transfer Protein Domain Containing 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Ceramide-1-Phosphate Transfer Protein; GlycolipidTransfer Protein Domain-Containing Protein 1; Glycolipid Transfer ProteinDomain Containing 1; GLTP Domain-Containing Protein 1; GLTPD1; GLTPD1; Ceramide-1-phosphatetransfer protein; CPTP. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLGTIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHWLQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRAVTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAEHSLLDLP. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
Formulation | GLTPD1 protein solution (0.25mg/ml) containing Phosphatebuffered saline (pH7.4), 50% glycerol and 1mM DTT. |
Glycolipid Transfer Protein Domain Containing 1 (GLTPD1) belongs to theGLTP family. GLTPD1 mediates the intracellular transfer of ceramide-1-phosphatebetween organelle membranes and the cell membrane. GLTPD1 is essential fornormal structure of the Golgi stacks. In addition, GLTPD1 is able to bindphosphoceramides with a diversity of aliphatic chains, however GLTPD1 has apreference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains.Moreover, GLTPD1 is inefficient with phosphoceramides which contains lignoceryl(C24:0). GLTPD1 participates in the regulation of the cellular levels ofceramide-1-phosphate, and in that way contributes to the regulation ofphospholipase PLA2G4A activity and the release of arachidonic acid.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.