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Estriol-d2 Sale

(Synonyms: 雌三醇 d2) 目录号 : GC45450

An internal standard for the quantification of estriol

Estriol-d2 Chemical Structure

Cas No.:53866-32-3

规格 价格 库存 购买数量
500μg
¥1,884.00
现货
1mg
¥3,255.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Estriol-d2 is intended for use as an internal standard for the quantification of estriol by GC- or LC-MS. Estriol is a metabolite of estradiol and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from <10 ng/ml at 8-10 weeks gestation to approximately 150 ng/ml at week 38.1 The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate and serves as a direct marker of fetal adrenal gland activity.2 Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels.2,3 Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.4

References
1. Peter, M., D•rr, H.G., and Sippell, W.G. Changes in the concentrations of dehydroepiandrosterone sulfate and estriol in maternal plasma during pregnancy: A longitudinal study in healthy women throughout gestation and at term. Hormone Research 42, 278-281 (1994).
2. Goodwin, T.M. A role for estriol in human labor, term and preterm. American Journal of Obstetics and Gynecology 180, S208-S213 (1999).
3. Voss, H.F. Hormonal pathways of preterm birth. American Journal of Obstetics and Gynecology 180, S226-S231 (1999).
4. . Steroid levels in humans. (1999).

Chemical Properties

Cas No. 53866-32-3 SDF
别名 雌三醇 d2
Canonical SMILES OC1=C([2H])C=C2C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])C[C@@H](O)[C@@H]4O)=C1[2H]
分子式 C18H22D2O3 分子量 290.4
溶解度 DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 5 mg/ml 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.4435 mL 17.2176 mL 34.4353 mL
5 mM 0.6887 mL 3.4435 mL 6.8871 mL
10 mM 0.3444 mL 1.7218 mL 3.4435 mL
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