FCER1A Human
目录号 : GP23476Fc-Epsilon RI-Alpha Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Fc Fragment Of IgE; High Affinity I; Receptor For; Alpha Polypeptide;FCE1A; IgE Fc Receptor Subunit Alpha; FcERI; Fc-Epsilon RI-Alpha; Fc Epsilon RIAlpha-Chain; Fc IgE Receptor; Alpha Polypeptide; High Affinity ImmunoglobulinEpsilon Receptor Alpha-Subunit; High Affinity Immunoglobulin Epsilon ReceptorSubunit Alpha; Immunoglobulin E Receptor; High-Affinity; Of Mast Cells; AlphaPolypeptide. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSVPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSEETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYKVIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | FCER1A protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. | ||
Fcfragment of IgE, high affinity I, receptor for; alpha polypeptide (FCER1A)binds to the Fc region of immunoglobulins epsilon. FCER1A is a high affinityreceptor. In addition FCER1A is responsible for starting the allergic response.Binding of allergen to receptor-bound IgE leads to cell activation and therelease of mediators such as histamine which is responsible for themanifestations of allergy. This receptor is contains of an alpha subunit, abeta subunit, and two gamma subunits. FCER1A stands for the alpha subunit.Among the diseases associated with FCER1A are mast-cell leukemia, and allergicasthma.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.