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Dodecylphosphocholine-d38

(Synonyms: 十二烷基磷酸胆碱-D38,n-Dodecylphosphocholine-d38) 目录号 : GC47259

An internal standard for the quantification of dodecylphosphocholine

Dodecylphosphocholine-d38 Chemical Structure

Cas No.:130890-78-7

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25 mg
¥1,181.00
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50 mg
¥2,244.00
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100 mg
¥4,249.00
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250 mg
¥9,456.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.1 It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.2 Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).3 Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.

1.Kurauskas, V., Hessel, A., Ma, P., et al.How detergent impacts membrane proteins: Atomic-level views of mitochondrial carriers in dodecylphosphocholineJ. Phys. Chem. Lett.9(5)933-938(2018) 2.Cady, S.D., Wang, J., Wu, Y., et al.Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopyJ. Am Chem. Soc.133(12)4274-4284(2011) 3.SauvÉ, S., and Aubin, Y.Dodecylphosphocholine micelles induce amyloid formation of the PrP(110-136) peptide via an α-helical metastable conformationPLoS One11(12)e0168021(2016)

Chemical Properties

Cas No. 130890-78-7 SDF
别名 十二烷基磷酸胆碱-D38,n-Dodecylphosphocholine-d38
化学名 2-[[(dodecyl-d25-oxy)hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-ethan-1,1,2,2-d4-aminium, inner salt
Canonical SMILES O=P(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[2H])([O-])OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
分子式 C17D38NO4P 分子量 389.7
溶解度 DMF: 16 mg/mL,DMSO: 16 mg/mL,Ethanol: 15 mg/mL,PBS (pH 7.2): 25 mg/ml 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
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1 mg 5 mg 10 mg
1 mM 2.5661 mL 12.8304 mL 25.6608 mL
5 mM 0.5132 mL 2.5661 mL 5.1322 mL
10 mM 0.2566 mL 1.283 mL 2.5661 mL
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