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Detomidine HCl Sale

(Synonyms: 盐酸地托咪定) 目录号 : GC17081

An α2-adrenoceptor agonist

Detomidine HCl Chemical Structure

Cas No.:90038-01-0

规格 价格 库存 购买数量
10mM (in 1mL DMSO) 待询 待询
10mg
¥450.00
现货
100mg
¥1,665.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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产品描述

Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonistTarget: α2-adrenergic agonistDetomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under the trade name Dormosedan. Currently, detomidine is only licenced for use in horses.Detomidine is a sedative with analgesic properties. α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.

References:
[1]. Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8(1):30-7.

Chemical Properties

Cas No. 90038-01-0 SDF
别名 盐酸地托咪定
化学名 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole;hydrochloride
Canonical SMILES CC1=C(C(=CC=C1)CC2=CN=CN2)C.Cl
分子式 C12H15ClN2 分子量 222.71
溶解度 ≥ 11.1mg/mL in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 4.4901 mL 22.4507 mL 44.9014 mL
5 mM 0.898 mL 4.4901 mL 8.9803 mL
10 mM 0.449 mL 2.2451 mL 4.4901 mL
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