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Deacetylanisomycin Sale

(Synonyms: 脱乙酰茴香霉素) 目录号 : GC52191

A derivative of anisomycin

Deacetylanisomycin Chemical Structure

Cas No.:27958-06-1

规格 价格 库存 购买数量
5 mg
¥3,410.00
现货
25 mg
¥15,354.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

Deacetylanisomycin is a derivative of the protein and DNA synthesis inhibitor anisomycin with antimalarial and anticancer activity.1,2 It inhibits the growth of the P. falciparum strains K1 and T9-96 in vitro (IC50s = 40.29 and 33.57 μM, respectively).1 Deacetylanisomycin is cytotoxic to LU99 lung carcinoma and MCF-7 breast cancer cells (IC50s = 23 and 34 μM, respectively). It has been used as a negative control for assessment of protein synthesis inhibitor activity in molluscan neurons.3

1.Ekong, R.M., Kirby, G.C., Patel, G., et al.Comparison of the in vitro activities of quassinoids with activity against Plasmodium falciparum, anisomycin and some other inhibitors of eukaryotic protein synthesisBiochem. Pharmacol.40(2)297-301(1990) 2.Hosoya, Y., Kameyama, T., Naganawa, H., et al.Anisomycin and new congeners active against human tumor cell linesJ. Antibiot. (Tokyo)46(8)1300-1302(1993) 3.Alkon, D.L., Bank, B., Naito, S., et al.Inhibition of protein synthesis prolongs Ca2+-mediated reduction of K+ currents in molluscan neuronsProc. Natl. Acad. Sci. USA84(19)6948-6952(1987)

Chemical Properties

Cas No. 27958-06-1 SDF Download SDF
别名 脱乙酰茴香霉素
Canonical SMILES COC(C=C1)=CC=C1C[C@@H]2[C@H](O)[C@@H](O)CN2
分子式 C12H17NO3 分子量 223.3
溶解度 Methanol: soluble 储存条件 Store at -20°C
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 4.4783 mL 22.3914 mL 44.7828 mL
5 mM 0.8957 mL 4.4783 mL 8.9566 mL
10 mM 0.4478 mL 2.2391 mL 4.4783 mL
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