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DBI Human

目录号 : GP23292

DBI Human Recombinant

DBI Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
25μg
¥2,030.00
5-10工作日
1mg
¥31,500.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

DBI Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 107 amino acids (1-87a.a.) and having a molecular mass of 12.2kDa. DBI protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.

Product Data

Purity Greater than 95% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms ACBP; ACBD1; CCK-RP; EP; DBI; EP; MGC70414; Acyl-CoA-binding protein; GABA receptor modulator.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF TGKAKWDAWN ELKGTSKEDA MKAYINKVEE LKKKYGI.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation DBI Human solution containing 20mM Tris-HCl pH-8, 0.1M NaCl & 10% glycerol.

Introduction

DBI, also known as Acyl-CoA-binding protein isoform 2, is abinding inhibitor, which is regulated by hormones. DBI participates in lipid metabolism and in the displacement of beta-carbolines & benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Moreover, during adipocyte differentiation the expression of DBI is significantly induced. DBI preforms as an acyl-CoA pool former and regulates LCFA (long-chain fatty acids) metabolism in peripheral tissues.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.