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CSDC2 Human

目录号 : GP23246

Cold Shock Domain Containing C2 Human Recombinant

CSDC2 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

CSDC2 Human Recombinant produced in E.coli is a single,non-glycosylated polypeptide chain containing 176 amino acids (1-153) andhaving a molecular mass of 19.2kDa. CSDC2 is fused to a 23 amino acid His-tagat N-terminus.

Product Data

Purity Greater than 90.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Cold shock domain-containing protein C2; RNA-bindingprotein PIPPin; PIPPIN; DJ347H13.2.
Amino Acid Sequence MGSSHHHHHHSSGLVPRGSH MGSMTSESTSPPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFSRSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWSGQVVGS.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation The CSDC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.

Introduction

Cold shock domain-containing protein C2 (CSDC2) is RNA-binding factor that binds specifically to the very 3'-UTR ends of both histone H1 and H3. 3 mRNAs encompass the polyadenylation signal. The CSDPs (cold shock domain containing proteins) are one group of the evolutionarily conserved nucleic acid-binding proteins extensively distributed in bacteria, plants, animals, and involved in a variety of cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. CSDC2 has a central role in the negative regulation of histone variant synthesis in the developing brain.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.