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CRYM Human

目录号 : GP23243

Crystallin, Mu Human Recombinant

CRYM Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥50,400.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

CRYM Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Ser2-Lys314) containing 322 amino acids including a 9 aa His tag at N-terminus. The total calculated molecular mass is 34.8kDa.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Synonyms Crystallin Mu; Thiomorpholine-Carboxylate Dehydrogenase; THBP; NADP-Regulated Thyroid-Hormone Binding Protein; NADP-Regulated Thyroid-Hormone-Binding Protein; Mu-Crystallin Homolog; EC 1.5.1.25; DFNA40; CRYM.
Amino Acid Sequence MKHHHHHHAS RVPAFLSAAE VEEHLRSSSL LIPPLETALA NFSSGPEGGV MQPVRTVVPV TKHRGYLGVM PAYSAAEDAL TTKLVTFYED RGITSVVPSH QATVLLFEPS NGTLLAVMDG NVITAKRTAA VSAIATKFLK PPSSEVLCIL GAGVQAYSHY EIFTEQFSFK EVRIWNRTKE NAEKFADTVQ GEVRVCSSVQ EAVAGADVII TVTLATEPIL FGEWVKPGAH INAVGASRPD WRELDDELMK EAVLYVDSQE AALKESGDVL LSGAEIFAEL GEVIKGVKPA HCEKTTVFKS LGMAVEDTVA AKLIYDSWSS GK.
Solubility It is recommended to add 200?l of deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. CRYM is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability Store lyophilized protein at -20°C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C .
Formulation CRYM was filtered (0.4µm) and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl, pH 7.5.

Introduction

Crystallin, Mu (CRYM) is a taxon-specific crystallin protein which binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. CRYM doesnбпt perform a structural role in lens tissue; instead CRYM binds thyroid hormone for possible regulatory or developmental roles. CRYM gene mutations are linked with autosomal dominant non-syndromic deafness. CRYM specifically catalyzes the reduction of imine bonds in brain substrates which may include cystathionine ketamine and lanthionine ketamine.

Stability

Store lyophilized protein at -20°C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C .