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CRISP3 Human

目录号 : GP23226

Cysteine-Rich Secretory Protein 3 Human Recombinant

CRISP3 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

CRISP3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (21-245) containing 235 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 26.74kDa.

Product Data

Purity Greater than 85.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Cysteine-Rich Secretory Protein 3; Specific Granule Protein of 28 KDa; CRISP-3; SGP28; Cysteine-Rich Secretory Protein-3; Specific Granule Protein (28 KDa); DJ442L6.3; CRS3; Aeg2; CRISP3.
Amino Acid Sequence MKHHHHHHASNEDKDPAFTA LLTTQTQVQR EIVNKHNELR RAVSPPARNM LKMEWNKEAA ANAQKWANQC NYRHSNPKDR MTSLKCGENL YMSSASSSWS QAIQSWFDEY NDFDFGVGPK TPNAVVGHYT QVVWYSSYLV GCGNAYCPNQ KVLKYYYVCQ YCPAGNWANR LYVPYEQGAP CASCPDNCDD GLCTNGCKYE DLYSNCKSLK LTLTCKHQLV RDSCKASCNC SNSIY.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CRISP3 filtered (0.4µm) solution at a concentration of 0.3mg/ml in 50mM acetate buffer pH 4, 5mM DTT and 20% glycerol.

Introduction

Cysteine-rich secretory protein 3 (CRISP3) is a member of the CRISP family of proteins having a pathogenesis related protein 1 (PR1) domain at its N-terminal and ion channel regulatory (ICR) domain at its C-terminal linked by a hinge region. CRISP3 transcripts are present predominantly in the prostate. CRISP3 expression is low in benign prostatic epithelium but is highly upregulated in the majority of high-grade prostatic intraepithelial neoplasia lesions and in most primary prostate tumors and metastases. CRISP3 is one of the genes which are most often upregulated in prostate cancer. Human Prostate Secretory Protein (PSP94 binds human CRISP3 with a very high affinity.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.