CDH5 Mouse
目录号 : GP23106Cadherin 5 Mouse Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 90.0% as determined by SDS-PAGE. | Source | Sf9, Insect cells. |
| Phycical Appearance | Sterilefiltered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Cadherin-5;Vascular endothelial cadherin; VE-cadherin; CD144; Cdh5. | ||
| Amino Acid Sequence | GPNFPQIDTP NMLPAHHRQK RDWIWNQMHI DEEKNESLPHYVGKIKSNVN RQNAKYVLQG EFAGKIFGVD ANTGNVLAYE RLDREKVSEY FLTALIVDKN TNKNLEQPSSFTVKVHDIND NWPVFSHQVF NASVPEMSAI GTSVIRVTAV DADDPTVAGH ATVLYQIVKG NEYFSIDNSGLIFTKIKNLD REKQAEYKIV VETQDALGLR GESGTATVMI RLEDINDNFP VFTQSTYTFS VPEDIRVGKPLGFLTVVDPD EPQNRMTKYS IMQGEYRDTF TIETDPKRNE GIIKPTKSLD YEVIQQYTFY IEATDPTIRYEYLSSTSGKN KAMVTINVLD VDEPPVFQRH FYHFKLPENQ KKPLIGTVVA KDPDKAQRSI GYSIRKTSDRGQFFRITKQG NIYNEKELDR ETYAWYNLTV EANELDSRGN PVGKESIVQV YIEVLDENDN PPEFAQPYEPKVCENAAQGK LVVQISATDK DVVPVNPKFK FALKNEDSNF TLINNHDNTA NITVKYGQFN REHAKFHYLPVLISDNGVPS LTGTSTLTVG VCKCNEQGEF TFCEEMAAQA GVSIQLEHHH HHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | CDH5 protein solution (0.5mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. | ||
Cadherin-5, also known as CDH5 is a classical cadherin which belongs tothe cadherin superfamily. The CDH5 is located in a six-cadherincluster in a region on the long arm of chromosome 16 which is involved in lossof heterozygosity events in breast as well as prostate cancer.CDH5 is a calcium-dependent cell-cell adhesion glycoproteincomposed of five extracellular cadherin repeats, a transmembrane region and ahighly conserved cytoplasmic tail. Furthermore, CDH5 functionsas a classic cadherin by passing on to cells the ability to adhere in a homophilic manner, CDH5plays a significant role in endothelial cell biology through control ofthe cohesion as well as organization of the intercellular junctions.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.