BRD2 Human
目录号 : GP22896Bromodomain Containing 2 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Bromodomain Containing 2; RING3; Really Interesting NewGene 3 Protein; Bromodomain-Containing 2; O27.1.1; FSRG1; Female Sterile Homeotic-RelatedGene 1; Bromodomain-Containing Protein 2; KIAA9001; D6S113E; RNF3; FSH; NAT;Bromodomain-containing protein 2 . | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMLQNVTP HNKLPGEGNA GLLGLGPEAA APGKRIRKPS LLYEGFESPTMASVPALQLT PANPPPPEVS NPKKPGRVTN QLQYLHKVVM KALWKHQFAW PFRQPVDAVK LGLPDYHKIIKQPMDMGTIK RRLENNYYWA ASECMQDFNT MFTNCYIYNKPTDDIVLMAQ TLEKIFLQKV ASMPQEEQEL VVTIPKNSHK KGAKLAALQGSVTSAHQVPA VSSVSHTALY TPPPEIPTTV LNIPHPSVIS SPLLKSLHSA GPPLLAVTAA PPAQPLAKKKGVKRKADTTT PTPTAILAPG SPASPPGSLE PKAARLPPMR RESGRPIKPP RKDLPDSQQQHQSSKKGKLS EQLKHCNGIL KELLSKKHAA YAWPFYKPVD ASALGLHDYHDIIKHPMDLS TVKRKMENRD YRDAQEFAAD VRLMFSNCYK YNPPDHDVVA MARKLQDVFE FRYAKMPD. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | BRD2 protein solution (1mg/ml) containing Phosphatebuffered saline (pH7.4), 10% glycerol and 1mM DTT. | ||
Bromodomain Containing 2, also known as BRD2 is a transcriptionalregulator which is a member of the BET, bromodomains and extra terminal domain, family ofroteins. BRD2 links with transcription complexes and it acetylated chromatin inthe course of mitosis, and it selectively binds o the acetylated lysine-12 residue ofhistone H4 through its two romodomains. BRD2 maps to the majorhistocompatability complex MHC) class IIregion on chromosome 6p21.3, however sequence comparisonadvocate that the protein is not implicated in the immune response. BRD2has been implicated in juvenilemyoclonic epilepsy, a common form of epilepsy which grows to be visible inadolescence.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.