BMP4 Human, CHO
目录号 : GP20104骨形态发生蛋白 4 活性人重组体，CHO
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | CHO cells. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | BMP4; ZYME; BMP2B; BMP2B1. | ||
| Amino Acid Sequence | SPKHHSQRAR KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAI VQT LVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR. | ||
| Solubility | It is recommended to reconstitute the lyophilized BMP4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized BMP4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution BMP4 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50, as calculated by Alkaline phosphatase activity induced in ATDC-5 cells is less than 15ng/ml corresponding to a specific activity which is > 6.7 x 10^4 units/mg. | ||
| Formulation | The protein was lyophilized from a sterile (0.2µm) filtered solution containing 0.1% Trifluoroacetic Acid (TFA). | ||
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
The ED50, as calculated by Alkaline phosphatase activity induced in ATDC-5 cells is less than 15ng/ml corresponding to a specific activity which is > 6.7 x 10^4 units/mg.
Lyophilized BMP4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution BMP4 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.