Batroxobin
目录号 : GP22840Batroxobin
Sample solution is provided at 25 µL, 10mM.
Batroxobin, isolated from Bothrops atrox snake venom, has an Mw of approximately 43kDa.
Purity | Source | ||
Phycical Appearance | Sterile Filtered white lyophilized powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | Thrombin-like enzyme batroxobin; EC 3.4.21.74; BX; Bothrops atrox serine proteinase; Venombin-A; Defibrase; Reptilase; Batroxobin. | ||
Solubility | It is recommended to reconstitute the lyophilized Batroxobin in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
Stability | Store the lyophilized Batroxobin between 2-8°C. Do not freeze! | ||
Formulation | The Batroxobin protein was lyophilized from a concentrated (1mg/ml) solution with no additives. |
Batroxobin is a serin protease that reduces fibronogen levels and is originally extracted from snake venom of Bothrops Atrox. Batroxobin is used in defibrinogenation and thrombolysis and also has an effect on c-fos gene and growth factor.Batroxobin can efficiently restrain proliferation of VSMCs, by blocking the release and uptake of Ca2+, thus influencing [Ca2+]i.Batroxobin converts fibrinogen to fibrin through the restricted release of fibrinopeptide-A from fibrinogen to promote blood to clot. Unlike thrombin, it is not affected by heparin and hirudin.
Store the lyophilized Batroxobin between 2-8°C. Do not freeze!