6-Methylpterin |
目录号 GC49864 |
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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Purity: >98.00%
- COA (Certificate Of Analysis)
- Datasheet
6-Methylpterin is a derivative of the essential B vitamin folic acid .1 It generates singlet oxygen and hydrogen peroxide when exposed to photoirradiation in cell-free assays.2 6-Methylpterin has been used as an internal standard for the detection of pterins in urine.3
1.Tsyupka, D.V., Mordovina, E.A., Sindeeva, O.A., et al.High-fluorescent product of folic acid photodegradation: Optical properties and cell effectJ. Photochem. Photobiol. A Chem.407113045(2021) 2.Cabrerizo, F.M., Lorente, C., Vignoni, M., et al.Photochemical behavior of 6-methylpterin in aqueous solutions: Generation of reactive oxygen speciesPhotochem. Photobiol.81(4)793-801(2005) 3.GirÓn, A.J., MartÍn-Tornero, E., SÁnchez, M.C.H., et al.A simple HPLC-ESI-MS method for the direct determination of ten pteridinic biomarkers in human urineTalanta101465-472(2012)
Cas No. | 708-75-8 | SDF | Download SDF |
别名 | N/A | ||
化学名 | N/A | ||
Canonical SMILES | O=C1N=C(N)N=C2NC=C(C)N=C21 | ||
分子式 | C7H7N5O | 分子量 | 177.2 |
溶解度 | DMF: Slightly soluble,DMSO: Slightly soluble,Ethanol: Slightly soluble,PBS (pH 7.2): Slightly soluble,Water: Slightly soluble | 储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % ddH2O | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL ddH2O,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。