| MPP+ Iodide 目录号 GC18188 |
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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Purity: >98.00%
- COA (Certificate Of Analysis)
- Datasheet
| Cas No. | 36913-39-0 | SDF | Download SDF |
| 别名 | N/A | ||
| 化学名 | 1-methyl-4-phenyl-pyridinium, monoiodide | ||
| Canonical SMILES | C[N+](C=C1)=CC=C1C2=CC=CC=C2.[I-] | ||
| 分子式 | C12H12N.I | 分子量 | 297.1 |
| 溶解度 | 100 mM in Water | 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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MPP+ is an active metabolite of MPTP , a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative stress. The key features of different neurotoxic models of Parkinson’s disease, including the MPTP model, have been detailed.