|Gly-Pro-pNA (hydrochloride) 目录号 GC18201|
Sample solution is provided at 25 µL, 10mM.
|Cas No.||103213-34-9||SDF||Download SDF|
|溶解度||30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol||储存条件||Store at -20°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
Gly-Pro-pNA is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm. DPP IV inactivates the two peptides responsible for a majority of nutrient-stimulated insulin secretion: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1). This substrate can be used to screen for DPP IV inhibitors, which have emerged as a new class of experimental antidiabetic agents.