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Gly-Pro-pNA (hydrochloride) 目录号 GC18201

A substrate for DPP IV

规格 价格 库存 购买数量
10mg
¥364.00
现货
25mg
¥819.00
现货
50mg
¥1,547.00
现货
100mg
¥2,912.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 103213-34-9 SDF Download SDF
别名 N/A
化学名 glycyl-N-(4-nitrophenyl)-L-prolinamide, monohydrochloride
Canonical SMILES O=C(CN)N1CCC[C@H]1C(NC2=CC=C([N+]([O-])=O)C=C2)=O.Cl
分子式 C13H16N4O4.HCl 分子量 328.8
溶解度 30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

Gly-Pro-pNA is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm. DPP IV inactivates the two peptides responsible for a majority of nutrient-stimulated insulin secretion: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1). This substrate can be used to screen for DPP IV inhibitors, which have emerged as a new class of experimental antidiabetic agents.