| Gly-Pro-pNA (hydrochloride) 目录号 GC18201 |
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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Purity: >98.00%
- COA (Certificate Of Analysis)
- Datasheet
| Cas No. | 103213-34-9 | SDF | Download SDF |
| 别名 | N/A | ||
| 化学名 | glycyl-N-(4-nitrophenyl)-L-prolinamide, monohydrochloride | ||
| Canonical SMILES | O=C(CN)N1CCC[C@H]1C(NC2=CC=C([N+]([O-])=O)C=C2)=O.Cl | ||
| 分子式 | C13H16N4O4.HCl | 分子量 | 328.8 |
| 溶解度 | 30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol | 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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Gly-Pro-pNA is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm. DPP IV inactivates the two peptides responsible for a majority of nutrient-stimulated insulin secretion: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1). This substrate can be used to screen for DPP IV inhibitors, which have emerged as a new class of experimental antidiabetic agents.