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BMPO 目录号 GC41397

规格 价格 库存 购买数量
5mg
¥1,235.00
现货
10mg
¥1,729.00
现货
25mg
¥3,705.00
现货
50mg
¥6,175.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 387334-31-8 SDF Download SDF
别名 BocMPO
化学名 3,4-dihydro-2-methyl-1,1-dimethylethyl ester-2H-pyrrole-2-carboxylic acid-1-oxide
Canonical SMILES [O-][N+]1=CCCC1(C)C(OC(C)(C)C)=O
分子式 C10H17NO3 分子量 199.2
溶解度 33mg/mL in ethanol, 25mg/mL in DMSO, or in DMF 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

BMPO is a cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo. The BMPO-superoxide adduct does not rapidly decompose to the hydroxyl adduct in cells (t½ = 23 min).[1][2] Also, the ESR spectrum of the BMPO-glutathionyl adduct does not fully overlap with the spectrum of its hydroxyl adduct. Purified by crystallization and stored as a solid, BMPO has a longer shelf life than liquid spin traps.[2]

Reference:
[1]. Zhao, H., Joseph, J., Zhang, H., et al. Synthesis and biochemical applications of a solid cyclic nitrone spin trap: A relatively superior trap for detecting superoxide anions and glutathiyl radicals. Free Radic. Biol. Med. 31(5), 599-606 (2001).
[2]. Khan, N., Wilmont, C.M., Rosen, G.M., et al. Spin traps: In vitro toxicity and stability of radical adducts. Free Radical Biology & Medicine 34(11), 1473-1481 (2003).