Home>>Signaling Pathways>> PROTAC>> PROTAC Linker>>2,2-Oxybis(ethylamine)
2,2-Oxybis(ethylamine) 目录号 GC60014

22-Oxybis(ethylamine) 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

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250mg
¥450.00
现货
500mg
¥630.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 2752-17-2 SDF Download SDF
别名 N/A
化学名 N/A
Canonical SMILES NCCOCCN
分子式 C4H12N2O 分子量 104.15
溶解度 N/A 储存条件 4°C, protect from light
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562