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TAK1 (transforming growth factor β-activated kinase-1) is an essential regulator of dendritic cell survival and immune system homeostasis and function.

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  2. GC13514 NG25 NG25 是一种有效的 TAK1 和 MAP4K2 双重抑制剂,IC50 分别为 149 nM 和 21.7 nM。

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