Serine Protease(丝氨酸蛋白酶)
Serine proteases, named for the nucleophilic Ser residue at the active site, are a large and diverse group of proteases (accounting for approximately one-third of all proteases) that are characterized by the presence of the Asp-His-Ser “charge relay” system (catalytic triad) in their chemical structures. However, with the development of technology, a variety of novel serine proteases with catalytic triads and dyads have been discovered, including Ser-His-Glu, Ser-Lys/His, His-Ser-His and N-terminal Ser. Serine proteases are traditionally divided into four clans based on the Asp-His-Ser triad in different structural contexts, including chymotrypsin-like proteases, subtilisin-like proteases, carboxypeptidase Y-like proteases and Clp protease-like proteases.
Products for Serine Protease
- Cat.No. 产品名称 Information
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GC26017
UK-371804 HCl
UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
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GC49221
QLT0267
An ILK inhibitor
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GC15682
Chymostatin
胰凝乳蛋白酶抑制剂
A potent inhibitor of chymotrypsin and chymase -
GC13967
Tosyllysine Chloromethyl Ketone (hydrochloride)
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐,1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone,TLCK
A non-selective proteinase inhibitor -
GC13421
UCF 101
An Omi/HtrA2 protease inhibitor
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GC17711
PPACKII (trifluoroacetate salt)
H-D-Phe-Phe-Arg-Chloromethyl Ketone
An irreversible inhibitor of kallikreins -
GC10477
PMSF
苯甲基磺酰氟; Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride
PMSF是一种不可逆的丝氨酸蛋白酶抑制剂,常被加入细胞或组织裂解液中以预防蛋白的降解。
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GC10613
Nafamostat Mesylate(FUT-175)
甲磺酸萘莫司他; FUT-175
A serine protease inhibitor -
GC12900
Aprotinin
抑肽酶
A serine protease inhibitor
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GC14502
AEBSF.HCl
4-(2-氨乙基)苯磺酰氟盐酸盐,AEBSF.HCl,AEBSF Hydrochloride
AEBSF.HCl是丝氨酸蛋白酶广谱的不可逆的抑制剂,可抑制胰凝乳蛋白酶,激肽释放酶,纤溶酶,凝血酶,胰蛋白酶和相关的溶栓酶等。
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GC10027
Leupeptin, Microbial
亮肽素
A reversible protease inhibitor