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Serine Protease(丝氨酸蛋白酶)

Serine proteases, named for the nucleophilic Ser residue at the active site, are a large and diverse group of proteases (accounting for approximately one-third of all proteases) that are characterized by the presence of the Asp-His-Ser “charge relay” system (catalytic triad) in their chemical structures. However, with the development of technology, a variety of novel serine proteases with catalytic triads and dyads have been discovered, including Ser-His-Glu, Ser-Lys/His, His-Ser-His and N-terminal Ser. Serine proteases are traditionally divided into four clans based on the Asp-His-Ser triad in different structural contexts, including chymotrypsin-like proteases, subtilisin-like proteases, carboxypeptidase Y-like proteases and Clp protease-like proteases.

Products for  Serine Protease

  1. Cat.No. 产品名称 Information
  2. GC26017 UK-371804 HCl UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
  3. GC49221 QLT0267 An ILK inhibitor
  4. GC15682 Chymostatin


    A potent inhibitor of chymotrypsin and chymase
  5. GC13967 Tosyllysine Chloromethyl Ketone (hydrochloride)


    A non-selective proteinase inhibitor
  6. GC13421 UCF 101 An Omi/HtrA2 protease inhibitor
  7. GC17711 PPACKII (trifluoroacetate salt)

    H-D-Phe-Phe-Arg-Chloromethyl Ketone

    An irreversible inhibitor of kallikreins
  8. GC10477 PMSF

    苯甲基磺酰氟; Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride


  9. GC10613 Nafamostat Mesylate(FUT-175)

    甲磺酸萘莫司他; FUT-175

    A serine protease inhibitor
  10. GC12900 Aprotinin


    A serine protease inhibitor

  11. GC14502 AEBSF.HCl

    4-(2-氨乙基)苯磺酰氟盐酸盐,AEBSF.HCl,AEBSF Hydrochloride


  12. GC10027 Leupeptin, Microbial


    A reversible protease inhibitor

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