Serine Protease(丝氨酸蛋白酶)
Serine proteases, named for the nucleophilic Ser residue at the active site, are a large and diverse group of proteases (accounting for approximately one-third of all proteases) that are characterized by the presence of the Asp-His-Ser “charge relay” system (catalytic triad) in their chemical structures. However, with the development of technology, a variety of novel serine proteases with catalytic triads and dyads have been discovered, including Ser-His-Glu, Ser-Lys/His, His-Ser-His and N-terminal Ser. Serine proteases are traditionally divided into four clans based on the Asp-His-Ser triad in different structural contexts, including chymotrypsin-like proteases, subtilisin-like proteases, carboxypeptidase Y-like proteases and Clp protease-like proteases.
- Cat.No. 产品名称 Information
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GC26017
UK-371804 HCl
UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
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GC49221
QLT0267
An ILK inhibitor
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GC15682
Chymostatin
A potent inhibitor of chymotrypsin and chymase
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GC13967
Tosyllysine Chloromethyl Ketone (hydrochloride)
A non-selective proteinase inhibitor
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GC13421
UCF 101
An Omi/HtrA2 protease inhibitor
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GC17711
PPACKII (trifluoroacetate salt)
An irreversible inhibitor of kallikreins
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GC10477
PMSF
A nonspecific, irreversible serine protease inhibitor
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GC10613
Nafamostat Mesylate(FUT-175)
A serine protease inhibitor
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GC12900
Aprotinin
A serine protease inhibitor
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GC14502
AEBSF.HCl
An irreversible serine protease inhibitor
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GC10027
Leupeptin, Microbial
A reversible protease inhibitor