Home >> Signaling Pathways >> Proteases >> Aminopeptidase


Aminopeptidases are a group of enzymes widely distributed among bacteria, fungi, animals and plants that catalyze the cleavage of amino acids from the amino terminus of protein or peptide substrates through hydrolysis of peptide bonds near the N-terminal end of a polypeptide chain.  Most aminopeptidases are assembled by relatively high mass (50kDa) subunits exhibiting multimeric structures, whereas some are monomeric. The majority of aminopeptidases are zinc metalloenzymes and hence inhibited by the transition-state analog bestatin.  Aminopeptidases have been found in many subcellular organelles as well as in cytoplasm and membrane, where they are involved in diverse proteolytic pathways and play an essential role in protein maturation, degradation of non-hormonal and hormonal peptides and possibly determination of protein stability.

  1. Cat.No. 产品名称 Information
  2. GC67997 Aminopeptidase-IN-1
  3. GC63435 LTA4H-IN-1 An inhibitor of LTA4 hydrolase
  4. GC62113 Firibastat
  5. GC36733 NGR peptide Trifluoroacetate
  6. GC35499 Bestatin trifluoroacetate An aminopeptidase inhibitor
  7. GC42777 Amastatin (hydrochloride) An aminopeptidase inhibitor
  8. GC34613 HFI-142
  9. GC18471 DG-051 An LTA4 hydrolase inhibitor
  10. GC16829 Arphamenine B (hemisulfate) An inhibitor of aminopeptidase B
  11. GC13454 L-Leucine 4-methoxy-β-naphthylamide (hydrochloride) An aminopeptidase substrate
  12. GC12732 TNP-470 An inhibitor of angiogenesis
  13. GC16350 Actinonin An aminopeptidase inhibitor
  14. GC15577 Bestatin hydrochloride An aminopeptidase inhibitor
  15. GC18011 SC 57461A A potent, orally active inhibitor of LTA4 hydrolase
  16. GC12358 Fumagillin A fungal metabolite with diverse biological activities
  17. GC10171 Puromycin aminonucleoside A glomerular epithelial cell toxin
  18. GC10406 Tosedostat (CHR2797) An aminopeptidase inhibitor
  19. GC11780 Bestatin An aminopeptidase inhibitor

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