NAE(NEDD8 活化酶)
NAE (NEDD8-activating enzyme) catalyzes the initial step of the neddylation signaling that regulates CRLs (cullin-ring ubiquitin ligases) activities. Its downstream effect is linked to cancer cell growth and survival.
- Cat.No. 产品名称 Information
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GC15086
MLN4924
A selective inhibitor of NEDD8-activating enzyme
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GC12175
MLN4924 HCl salt
A selective inhibitor of NEDD8-activating enzyme