NAE (NEDD8-activating enzyme) catalyzes the initial step of the neddylation signaling that regulates CRLs (cullin-ring ubiquitin ligases) activities. Its downstream effect is linked to cancer cell growth and survival.
- Cat.No. 产品名称 Information
- GC15086 MLN4924 A selective inhibitor of NEDD8-activating enzyme
- GC12175 MLN4924 HCl salt A selective inhibitor of NEDD8-activating enzyme