Nampt(烟酰胺磷酸核糖转移酶)
Nampt (nicotinamide phosphoribosyltransferase) catalyzes the nicotinamide condensation with 5-phosphoribosyl-1-pyrophosphate to produce nicotinamide mononucleotide during the nicotinamide adenine dinucleotide biosynthesis. It is involved in the metabolism, stress response and aging.
- Cat.No. 产品名称 Information
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GC16709
CB 300919
CB 300919 是一种基于喹唑啉的抗肿瘤剂,在 CH1 人类卵巢肿瘤异种移植物中具有高活性。 CB 300919 在人类 CH1 卵巢肿瘤异种移植物中的持续暴露(96 小时)生长抑制 IC50 值为 2 nM。
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GC15207
CB30865
CB30865 (ZM 242421) 是一种烟酰胺磷酸核糖基转移酶 (Nampt) 抑制剂,具有强细胞毒性。 CB30865 对多种人类肿瘤细胞系非常有效(IC50 值在 1-10 nM 范围内)。
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GC14308
FK866 (APO866)
Inhibitor of nicotinamide phosphoribosyltransferase
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GC14815
GMX1778 (CHS828)
A pyridyl cyanoguanidine anti-tumor agent
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GC16041
GNE-617
A potent Nampt inhibitor
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GC15967
GNE-617 hydrochloride
A potent Nampt inhibitor
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GC41308
GPP 78
Inhibitor of Nampt
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GC14615
KPT-9274
Orally acitve allosteric inhibitor of PAK4
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GC36429
LB-60-OF61
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GC32818
Nampt-IN-1 (LSN3154567)
A potent Nampt inhibitor
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GC36690
Nampt-IN-3
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GC62476
Nampt-IN-5
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GC67797
NAT
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GC14692
P7C3
A proneurogenic and neuroprotective compound
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GC37602
SBI-797812
SBI-797812 is a NAMPT activator which is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 turns NAMPT into a "super catalyst" that more efficiently generates NMN.
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GC17096
STF-118804
A Nampt inhibitor
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GC61622
Teglarinad chloride