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FBPase (Fructose-1,6-bisphosphatase) is a rate-limiting enzyme of gluconeogesis that catalyze the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. It functions in pancreatic beta-cell glucose sensing and insulin secretion and link to hypoglycemia and metabolic acidosis.

  1. Cat.No. 产品名称 Information
  2. GC16703 Fructose 1,6-bisphosphatase-1 Inhibitor Fructose 1,6-bisphosphatase-1 Inhibitor (compound 1) 是果糖 1,6-bisphosphatase (FBPase-1) 的变构抑制剂。
  3. GC12084 MB05032 MB05032 是一种特殊且有效的糖异生抑制剂,靶向果糖 1,6-双磷酸酶 (FBPase) 的 AMP 结合位点,IC50 值为 16 nM。

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