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Rac is a member of the RAS superfamily of small GTPase. It functions in various cellular processes including regulation of secretory processes, membrane ruffles, cell polarization and phagocytosis of apoptotic cells etc. It is contributed to malignant progression.

  1. Cat.No. 产品名称 Information
  2. GC10030 EHop-016 EHop-016 是一种有效的选择性 Rac GTPase Rac1 和 Rac3 抑制剂。 EHop-016 在 MDA-MB-435 细胞中抑制 Rac1 活性,IC50 为 1.1 μM。 EHop-016 抑制 Vav2 与 Rac、Rac 激活的 PAK1、片状伪足形成和细胞迁移的相互作用。
  3. GC10069 NSC 23766 trihydrochloride NSC 23766 trihydrochloride 是 Rac1 活化的抑制剂。

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