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Home >> Signaling Pathways >> MAPK Signaling >> MNK

MNK(丝裂原活化蛋白激酶相互作用激酶)

MNK (MAP kinase-interacting kinases) is a group of serine/threonine kinase that phosphorylates eukaryotic initiation factor 4E (eIF4E) in the MAPK signaling pathways. It plays an important role in cell transformation and tumor progression.

  1. Cat.No. 产品名称 Information
  2. GC69013 DS12881479 DS12881479 是一种有效的选择性 Mnk1 抑制剂，其 IC50 值为21 nM. DS12881479 可用于癌症研究。
  3. GC33033 ETC-206 An inhibitor of MKNK1 and MKNK2
  4. GC32937 SLV-2436 (SEL201-88) SEL-201 (SLV-2436, SEL201-88) is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 ?nM and 5.4 nM, respectively.
  5. GC19131 Tomivosertib A potent inhibitor of MNK1 and MNK2
  6. GC10666 CGP 57380 Inhibitor of MAPK-interacting kinase1
  7. GC15391 Cercosporamide A potent inhibitor of fungal Pkc1 and mammalian Mnk isoforms

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