Sigma Receptor(Sigma受体)

Sigma receptors are non-opioid receptors that interacted with psychostimulants such as cocaine and methamphetamine. It is associated with central nervous systems diseases, cancer and neuropathic pain etc.

Products for Sigma Receptor

Cat.No. 产品名称 Information
GC10407 S1RA A σ₁ receptor antagonist
GC13083 Siramesine A selective σ₂ receptor agonist
GC15222 Siramesine hydrochloride Siramesine (Lu 28-179) hydrochloride 是一种有效的 sigma-2 受体激动剂。 Siramesine hydrochloride 对 sigma-2 受体具有亚纳摩尔亲和力 (IC50=0.12 nM)，对 sigma-2 受体的选择性是 sigma-1 受体的 140 倍 (IC50=17 nM)。盐酸西拉美新通过破坏线粒体而不是溶酶体触发细胞死亡。抗癌活性。