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(Z)-Aconitic acid Sale

(Synonyms: 顺乌头酸; cis-Aconitic acid) 目录号 : GC38304

Cis-Aconitic acid (cis-aconitate, Achilleic acid, Citridinic acid, Equisetic acid, Pyrocitric acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.

(Z)-Aconitic acid Chemical Structure

Cas No.:585-84-2

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产品描述

Cis-Aconitic acid (cis-aconitate, Achilleic acid, Citridinic acid, Equisetic acid, Pyrocitric acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.

Chemical Properties

Cas No. 585-84-2 SDF
别名 顺乌头酸; cis-Aconitic acid
Canonical SMILES O=C(O)/C([H])=C(C(O)=O)/CC(O)=O.
分子式 C6H6O6 分子量 174.11
溶解度 Water: 100 mg/mL (574.35 mM); DMSO: ≥ 100 mg/mL (574.35 mM) 储存条件 Store at -20°C
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 5.7435 mL 28.7175 mL 57.435 mL
5 mM 1.1487 mL 5.7435 mL 11.487 mL
10 mM 0.5743 mL 2.8717 mL 5.7435 mL
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Research Update

A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

Z Naturforsch C J Biosci 2017 Oct 26;72(11-12):477-482.PMID:28525357DOI:10.1515/znc-2017-0027.

Phytochemical investigation of the aerial parts of Sansevieria trifasciata, one of the most common Dracaenaceae plants, has resulted in the isolation of a new dihydrochalcone derivative named trifasciatine C (1), four previously unreported steroidal saponins as two pairs of inseparable regioisomers: trifasciatosides K/L (2/3), M/N (4/5), together with the known 1,2-(dipalmitoyl)-3-O-β-D-galactopyranosylglycerol (6), aconitic acid (7), and 1-methyl aconitic acid (8). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D nuclear magnetic resonance) and high-resolution electronspray ionization-mass spectrometry, as well as chemical methods and comparison of their spectral data with those of related compounds. Compounds 2/3 and 4/5 were evaluated for their antiproliferative activity on Hela cells, and no significant effect was observed.

Antifeedants of Indian barnyard millet, Echinochloa frumentacea link, against brown planthopper, Nilaparvata lugens (Stål)

Z Naturforsch C J Biosci 2008 Sep-Oct;63(9-10):755-60.PMID:19040117DOI:10.1515/znc-2008-9-1022.

Eight compounds isolated from Indian barnyard millet have been identified as L-malic acid, trans-aconitic acid, (+)-isocitric acid, 5-O-caffeoylquinic acid, 4-O-caffeoylquinic acid, isocarlinoside, 2"-O-rhamnosylisoorientin, and 7-O-(2"-O-glucuronosyl)glucuronosyltricin, respectively. These compounds showed high antifeeding activity against brown planthopper only when they were combined.

Isolation, structure determination, and sensory activity of mouth-drying and astringent nitrogen-containing phytochemicals isolated from red currants (Ribes rubrum)

J Agric Food Chem 2007 Feb 21;55(4):1405-10.PMID:17261020DOI:10.1021/jf0632076.

Application of chromatographic separation and taste dilution analyses recently revealed, besides a series of flavon-3-ol glycosides and (E)/(Z)-Aconitic acid, four nitrogen-containing phytochemicals as the key astringent and mouth-drying compounds in red currants (Ribes rubrum). The isolation and structure determination of the astringent indoles 3-carboxymethyl-indole-1-N-beta-D-glucopyranoside (1) and 3-methylcarboxymethyl-indole-1-N-beta-D-glucopyranoside (2), as well as the astringent, noncyanogenic nitriles 2-(4-hydroxybenzoyloxymethyl)-4-beta-D-glucopyranosyloxy-2(E)-butenenitrile (3) and 2-(4-hydroxy-3-methoxybenzoyloxymethyl)-4-beta-D-glucopyranosyloxy-2(E)-butenenitrile (4) by means of 1D/2D NMR, LC-MS/MS, and UV-vis spectroscopy are reported. The structures of compounds 1 and 2 were confirmed by synthesis. Using the recently developed half-tongue test, human recognition thresholds for the astringent and mouth-drying nitrogen compounds were determined to be between 0.0003 and 5.9 micromol/L (water). In particular, the extraordinarily low threshold of 0.0003 micromol/L evaluated for the indole 1 represents the lowest recognition threshold of any astringent phytochemical reported to date.

[Organic acids in vegetables. I. Brassica, leaf and bulb vegetables as well as carrots and celery]

Z Lebensm Unters Forsch 1985 Mar;180(3):215-20.PMID:4002860DOI:10.1007/BF01027268.

18 German vegetable species were analyzed for their organic acid content. Organic acids were isolated by methanol extraction followed by ion exchange. After derivatisation with BSA the trimethylsilyl derivatives were analyzed by gas chromatography using SE-52 and OV-1701 glass capillaries. The predominate acids are malic and citric acid, and in most cases malic acid was the most abundant. Succinic, fumaric, and quinic acids are wide spread, tartaric acid was found in carrots, lettuce, endives, chicory, and celery. Other acids such as malonic, shikimic, and t-aconitic acids occurred sporadically. Lactic acid which was determined by two other methods was not detected in any vegetable species.

[Metabonomic profiling of plasma metabolites in Wistar rats to study the effect of aging by means of GC/TOFMS-based techniques]

Yao Xue Xue Bao 2009 Oct;44(10):1095-101.PMID:20055130doi

The global metabolite profiles of endogenous compounds of Wistar rats from 12 to 20 weeks old were investigated to take deep insight into and get better understanding of the pathogenesis of development and aging. Plasma from Wistar rats at 12, 14, 16, 18, and 20 weeks old were analyzed using GC/TOFMS. Multivariate data analysis was then used to process the metabonomic data which indicated excellent separation between different weeks and showed that the metabolic profiles of the samples changed with age, enabling age-related metabolic trajectories to be visualized. Decreased concentrations of citric acid, cis-aconitic acid, 9-(Z)-hexadecenoic acid along with increased levels of hexanedioic acid, alpha-tocopherol, 3-indole propionic acid, etc contributed to the separation. Several major metabolic pathways were identified to be involved in metabolic regulation. This suggests that GC/TOFMS-based metabonomics is a powerful alternative approach to identifying potential biomarkers and investigating the physiological developments of aging and it is important to employ suitable age-match control group in metabonomic study of physiological monitoring, drug safety assessment, and disease diagnosis, etc.