4-Methoxybenzaldehyde
(Synonyms: 4-甲氧基苯甲醛) 目录号 : GC35134
p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
Cas No.:123-11-5
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
| Cas No. | 123-11-5 | SDF | |
| 别名 | 4-甲氧基苯甲醛 | ||
| Canonical SMILES | O=CC1=CC=C(OC)C=C1 | ||
| 分子式 | C8H8O2 | 分子量 | 136.15 |
| 溶解度 | DMSO : 100mg/mL | 储存条件 | Store at 2-8°C, stored under nitrogen |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
||
| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 7.3448 mL | 36.7242 mL | 73.4484 mL |
| 5 mM | 1.469 mL | 7.3448 mL | 14.6897 mL |
| 10 mM | 0.7345 mL | 3.6724 mL | 7.3448 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Condensation Product of 4-Methoxybenzaldehyde and Ethylenediamine: "Off-On" Fluorescent Sensor for Cerium(III)
J Fluoresc 2018 Nov;28(6):1357-1361.PMID:30251063DOI:10.1007/s10895-018-2298-0.
The condensation product (L) of 4-Methoxybenzaldehyde and ethylenediamine has been synthesised and characterised. L showed a 21 times enhancement in fluorescence intensity on interaction with Ce3+ in CH3OH at λmax = 360 nm when excited with 270 nm photons. Metal ions K+, Na+, Al3+, Co2+, Hg2+, Cd2+, Ni2+, Zn2+, Mn2+, Mg2+ and Ca2+ do not interfere. The stoichiometry of binding and the binding constants were determined from spectroscopic data and found to be 1:1 and 104.8 M respectively. The detection limit was found to be 10-5.2 M. The protonation/de-protonation of water molecules coordinated to Ce3+ was found to show interesting behaviour on the fluorescence of L:Ce3+.
catena-Poly[copper(II)-di-μ-acetylacetonato-copper(II)-bis(μ-4-hydroxy-3-methoxybenzaldehyde picoloylhydrazonato)] and (acetylacetonato)(4-Methoxybenzaldehyde picoloylhydrazonato)copper(II)
Acta Crystallogr C 2010 Dec;66(Pt 12):m375-8.PMID:21123881DOI:10.1107/S0108270110044343.
In the two title copper(II) complexes, [CuL(C(5)H(7)O(2))](n), (I), and [CuL'(C(5)H(7)O(2))], (II), respectively, where HL is 4-hydroxy-3-methoxybenzaldehyde picoloylhydrazone, C(14)H(12)N(3)O(3), and HL' is 4-Methoxybenzaldehyde picoloylhydrazone, C(14)H(12)N(3)O(2), the Cu(II) ions display a highly Jahn-Teller-distorted octahedral and a square-planar coordination geometry, respectively. In complex (I), two neighbouring Cu(II) atoms are bridged by L(-) and acetylacetonate, alternately, giving rise to a one-dimensional chain of CuN(2)O(4) octahedra interconnected by these two ligands along the a axis. In addition, the hydroxy H atom of the vanillin group connects to the carboxyl O atom of the adjacent chain via an O-H...O hydrogen bond, giving rise to a three-dimensional supramolecular assembly. Complex (II) displays a discrete structure.
L-Chlorozotocin
J Med Chem 1979 May;22(5):597-9.PMID:156793DOI:10.1021/jm00191a030.
L-Chlorozotocin (2-[[[2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-L-glucose) was synthesized in seven steps from L-arabinose for comparison with chlorozotocin, which is the D enantiomorph and an antineoplastic agent with clinical potential. Purification of the intermediate 2-amino-2-deoxy-L-glucose as the Schiff's base formed with 4-Methoxybenzaldehyde ensured complete separation from the manno epimer. Comparative screening against leukemia L1210 with concurrent toxicity controls revealed no significant difference between D- and L-chlorozotocin in either activity or toxicity.
Using heavy atom rare gas matrix to control the reactivity of 4-Methoxybenzaldehyde: a comparison with benzaldehyde
J Chem Phys 2012 Apr 14;136(14):144509.PMID:22502535DOI:10.1063/1.3701734.
Different patterns of photochemical behavior were observed for 4-Methoxybenzaldehyde (p-anisaldehyde) isolated in xenon and in argon matrices. Monomers of the compound isolated in solid Xe decarbonylate upon middle ultraviolet irradiation, yielding methoxybenzene (anisole), and CO. On the other hand, p-anisaldehyde isolated in an Ar matrix and subjected to identical irradiation, predominantly isomerizes to the closed-ring isomeric ketene (4-methoxycyclohexa-2,4-dien-1-ylidene) methanone. Experimental detection of a closed-ring ketene photoproduct, generated from an aromatic aldehyde, constitutes a rare observation. The difference between the patterns of photochemical transformations of p-anisaldehyde isolated in argon and xenon environments can be attributed to the external heavy-atom effect, where xenon enhances the rate of intersystem crossing from the singlet to the triplet manifold in which decarbonylation (via p-methoxybenzoyl radical) takes place. The parent compound, benzaldehyde, decarbonylates (to benzene + CO) when subjected to middle ultraviolet irradiation in both argon and xenon matrices. This demonstrates the role of the methoxy p-anisaldehyde substituent in activation of the reaction channel leading to the formation of the ketene photoproduct.
Solvent-free condensation of phenylacetonitrile and nonanenitrile with 4-Methoxybenzaldehyde: optimization and mechanistic studies
Org Biomol Chem 2005 Apr 21;3(8):1534-40.PMID:15827653DOI:10.1039/b418156e.
The condensation of phenylacetonitrile with 4-Methoxybenzaldehyde can be carried out by two solvent-free methods: i) using neat powdered KOH at room temperature with equivalent amounts of aldehyde, nitrile and base for 3 min, and ii) using K2CO3 in the presence of a phase transfer agent for 3 min under microwave activation or conventional heating. By extending the reaction time up to 10 min, four different products were obtained from phenyl or nitrile group migration. With nonanenitrile, only the second method could be applied to give two kinds of condensed compounds with or without phenyl (or nitrile) group migration. The intervention of non-thermal MW-specific effects was proved in some cases and interpreted.