GH, Mouse
(Synonyms: GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin) 目录号 : GC26876生长激素（GH）是生长激素/催乳素家族的一员，在生长控制中起着重要作用。
Sample solution is provided at 25 µL, 10mM.
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Growth Hormone (GH), is a member of the somatotropin / prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
生长激素（GH）是生长激素/催乳素家族的一员，在生长控制中起着重要作用。该基因与其他四个相关基因一起位于17号染色体上的生长激素位点，在那里它们以相同的转录方向散布；一种被认为是由一系列基因复制进化而来的排列。这五个基因具有非常高的序列同一性。选择性剪接会产生五种生长激素中每一种的额外亚型，从而导致进一步的多样性和特化的潜力。这个特殊的家族成员在垂体中表达，但在胎盘组织中不表达，就像生长激素基因座中的其他四个基因一样。基因突变或缺失会导致生长激素缺乏和身材矮小。
| Purity |
> 95% as analyzed by SDS-PAGE > 95% as analyzed by SEC-HPLC |
Source | Mouse |
| Phycical Appearance | Shipping Condition | ||
| Synonyms | GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin | ||
| Apparent Molecular Weight | 22 kDa | ||
| Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. | ||
| Biological Activity | Recombinant mouse growth hormone is fully biologically active when compared to standard human growth hormone which is 3.0 units/mg. | ||
| Endotoxin Level | < 1 EU/μg of protein by LAL method | ||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile 18 MΩ-cm H₂O up to 100 µg/ml. | ||
| Formulation | Lyophilized after extensive dialysis against 50 mM Tris-HCl, pH 8.0, 500 mM NaCl buffer. | ||
Growth Hormone (GH), is a member of the somatotropin / prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Recombinant mouse growth hormone is fully biologically active when compared to standard human growth hormone which is 3.0 units/mg.
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.