Home>>Fmoc-Cys(4-methoxytrityl)-OH

Fmoc-Cys(4-methoxytrityl)-OH Sale

(Synonyms: N-芴甲氧羰基-S-(4-甲氧基三苯甲基)-L-半胱氨酸) 目录号 : GA21557

4-Methoxytrityl (Mmt) is a very acid-sensitive cysteine protecting group that can selectively be removed by 0.5-1.0% TFA in the presence of scavengers, e.g. TES. Protecting groups of the t-butyl type and S-Trt are left intact under these conditions. Cleavage and cyclization can be achieved concomitantly by adding iodine. It can be used in the solid-phase synthesis of cysteine-containing peptides, and further to selectively deprotect a thiol function in order to introduce a labeling group. Rijkers et al. employed p-methoxytrityl protection for obtaining S-palmitoylated peptides on-resin. The high acid lability of Cys(Mmt) was exploited by Roberts et al. to obtain a library of thioether-linked cyclic peptides. Arendt et al. employed Cys(Mmt) for the synthesis of peptides containing cysteic acid by selective deblocking and oxidation of the thiol moiety with performic acid. Mmt is fully stable to HOBt.

Fmoc-Cys(4-methoxytrityl)-OH Chemical Structure

Cas No.:177582-21-7

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1g
¥3,486.00
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5g
¥13,960.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

4-Methoxytrityl (Mmt) is a very acid-sensitive cysteine protecting group that can selectively be removed by 0.5-1.0% TFA in the presence of scavengers, e.g. TES. Protecting groups of the t-butyl type and S-Trt are left intact under these conditions. Cl

Chemical Properties

Cas No. 177582-21-7 SDF
别名 N-芴甲氧羰基-S-(4-甲氧基三苯甲基)-L-半胱氨酸
分子式 C38H33NO5S 分子量 615.76
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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1 mg 5 mg 10 mg
1 mM 1.624 mL 8.12 mL 16.2401 mL
5 mM 0.3248 mL 1.624 mL 3.248 mL
10 mM 0.1624 mL 0.812 mL 1.624 mL
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