Daphylloside
(Synonyms: 交让木苷) 目录号 : GC31939Daphylloside是从Galiumverum的地上部分分离的环烯醚萜苷。
Cas No.:14260-99-2
Sample solution is provided at 25 µL, 10mM.
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Daphylloside is an iridoid isolated from the aerial parts of Galium verum.
Daphylloside may show some antioxidant effects.
[1]. Demi?rezer LO, et al. Iridoids, Flavonoids and Monoterpene Glycosides from Galium verum subsp. verum. organic letters 1999 Vol. 1, No. 8 1169-1171. [2]. Raju BL, et al. Antioxidant iridoid glucosides from Wendlandia formosana. Nat Prod Res. 2004 Aug;18(4):357-64.
Cas No. | 14260-99-2 | SDF | |
别名 | 交让木苷 | ||
Canonical SMILES | OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2[C@@]3([H])[C@@]([C@@H](O)C=C3COC(C)=O)([H])C(C(OC)=O)=CO2 | ||
分子式 | C19H26O12 | 分子量 | 446.4 |
溶解度 | Soluble in DMSO | 储存条件 | Store at -20°C |
General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。 为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。 |
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制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 2.2401 mL | 11.2007 mL | 22.4014 mL |
5 mM | 0.448 mL | 2.2401 mL | 4.4803 mL |
10 mM | 0.224 mL | 1.1201 mL | 2.2401 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
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工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
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Iridoid glucosides from Wendlandia ligustroides (Boiss. &Hohen.) Blakelock
Eight iridoid glucosides were reported from the aerial parts of Wendlandia ligustroides. 10-deoxygeniposidic acid (1), 7-deoxygardoside (2), geniposidic acid (3), 7-deoxy-8-epi-loganic acid (4), deacetyl-daphylloside (5), scandoside methyl ester (6), 6-O-methyl-deacetyl-daphylloside (7), 6-O-methyl-scandoside methyl ester (8). Compounds 3 - 8 were isolated as a pure form while 1 and 2 as a mixture. The structures of the compounds 1 - 8 were established by spectroscopic methods including 1D-NMR (1H NMR, 13C NMR, DEPT-135), 2D-NMR (COSY, NOESY, HSQC, HMBC) and HRMS.
[Iridoids of Borreria verticillata]
Seven iridoids are isolated from Borreria verticillata root barks: daphylloside 1, asperuloside 2, feretoside 3, methyl desacetylasperulosidate 4, desacetylasperuloside 5, asperulosidic acid 6 and desacetylasperulosidic acid 7. Their structures result from spectroscopic analysis and are proved by chemical correlation.
Antioxidant iridoid glucosides from Wendlandia formosana
Two new iridoid glucosides of 10-O-caffeoyl scandoside methyl ester (3), and 6-methoxy scandoside methyl ester (4) besides the known compounds of scandoside methyl ester (1), methyl deacetyl asperulosidate (2), 10-O-caffeoyl daphylloside (5), phytol (6), and ursolic acid (7) were isolated from the leaves of Wendlandia formosana. Structure elucidation of the new iridoid glucosides was based on interpretation of high-resolution 1D and 2D NMR spectral data and chemical conversions. Antioxidant activity of Compounds (1-5) against diphenylpicrylhydrazyl (DPPH) and hydroxyl radical, and peroxynitrite was reported.
[Chemical Constituents from Oldenlandia diffusa]
Objective: To study the chemical constituents of water extracted fraction from Oldenlandia diffusa.
Methods: The compounds were isolated and purified by column chromatography on macroporous resin,silica gel,MCI gel,Sephadex LH-20,ODS medium pressure liquid chromatography and RP-semi-preparative HPLC. The structures of compounds were elucidated on the basis of physicochemical and spectral analysis.
Results: 16 compounds were isolated from the water extract of Oldenlandia diffusa,and their structures were identified as asperuloside( 1),deacetyl asperuloside( 2),geniposide( 3),10-dehydrogeniposide( 4),daphylloside( 5),diffusoside A( 6),diffusoside B( 7),coniferin( 8),scandoside methyl ester( 9),acetyl scandoside methyl ester( 10),deacetylasperulosidic acid methyl ester( 11),gardenoside( 12),galioside( 13),galioside 10-acetate( 14),loliolide( 15) and( +)-neo-olivil( 16),respectively.
Conclusion: Compounds 3,8 and 14 ~ 16 are obtained from Oldenlandia diffusa for the first time.
[Study on chemical constituents of iridoids from eucommiae folium]
Objective: To investigate the chemical constituents of iridoids from Eucommiae Folium.
Methods: The compounds were isolated and purified by various column chromatography, the structures were identified on the basis of physiochemical properties and spectral analysis.
Results: Nine iridoids were isolated and identified as asperuloside (1), daphylloside (2), scandoside methyl ester (3), loganin (4), 8-epi-loganin (5), 7-epi-loganin (6), deacetyl asperulosidic acid methyl ester (7), geniposide (8) and geniposidic acid (9).
Conclusion: Compounds 2 - 7 are isolated from this plant for the first time, compounds 4 - 6 are isolated from this genus for the first time.